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Topological constraints are major determinants of tRNA tertiary structure and dynamics and provide basis for tertiary folding cooperativity
Recent studies have shown that basic steric and connectivity constraints encoded at the secondary structure level are key determinants of 3D structure and dynamics in simple two-way RNA junctions. However, the role of these topological constraints in higher order RNA junctions remains poorly underst...
Autores principales: | Mustoe, Anthony M., Brooks, Charles L., Al-Hashimi, Hashim M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191394/ https://www.ncbi.nlm.nih.gov/pubmed/25217593 http://dx.doi.org/10.1093/nar/gku807 |
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