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Unraveling the sequence-dependent polymorphic behavior of d(CpG) steps in B-DNA

We have made a detailed study of one of the most surprising sources of polymorphism in B-DNA: the high twist/low twist (HT/LT) conformational change in the d(CpG) base pair step. Using extensive computations, complemented with database analysis, we were able to characterize the twist polymorphism in...

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Detalles Bibliográficos
Autores principales:	Dans, Pablo Daniel, Faustino, Ignacio, Battistini, Federica, Zakrzewska, Krystyna, Lavery, Richard, Orozco, Modesto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191396/ https://www.ncbi.nlm.nih.gov/pubmed/25223784 http://dx.doi.org/10.1093/nar/gku809

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