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Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA

Dengue virus nonstructural protein 3 (NS3) is a multifunctional protein formed by a superfamily-2 RNA helicase linked to a protease domain. In this work, we report results from in vitro experiments designed to determine the oligomeric state of dengue virus NS3 helicase (NS3h) and to characterize fun...

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Detalles Bibliográficos
Autores principales:	Gebhard, Leopoldo G., Incicco, J. Jeremías, Smal, Clara, Gallo, Mariana, Gamarnik, Andrea V., Kaufman, Sergio B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191397/ https://www.ncbi.nlm.nih.gov/pubmed/25223789 http://dx.doi.org/10.1093/nar/gku812

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