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Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase

In most organisms, the widely conserved 1-methyl-adenosine58 (m(1)A(58)) tRNA modification is catalyzed by an S-adenosyl-L-methionine (SAM)-dependent, site-specific enzyme TrmI. In archaea, TrmI also methylates the adjacent adenine 57, m(1)A(57) being an obligatory intermediate of 1-methyl-inosine57...

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Detalles Bibliográficos
Autores principales:	Hamdane, Djemel, Guelorget, Amandine, Guérineau, Vincent, Golinelli-Pimpaneau, Béatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191401/ https://www.ncbi.nlm.nih.gov/pubmed/25217588 http://dx.doi.org/10.1093/nar/gku820

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