Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression

Genome-wide distribution of histone H3K18 and H3K27 acetyltransferases, CBP (CREBBP) and p300 (EP300), is used to map enhancers and promoters, but whether these elements functionally require CBP/p300 remains largely uncertain. Here we compared global CBP recruitment with gene expression in wild-type...

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Detalles Bibliográficos
Autores principales: Kasper, Lawryn H., Qu, Chunxu, Obenauer, John C., McGoldrick, Daniel J., Brindle, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191404/
https://www.ncbi.nlm.nih.gov/pubmed/25249627
http://dx.doi.org/10.1093/nar/gku827

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