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Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome
In human chromosomes, centromeric regions comprise megabase-size arrays of 171 bp alpha-satellite DNA monomers. The large distances spanned by these arrays preclude their replication from external sites and imply that the repetitive monomers contain replication origins. However, replication within t...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191410/ https://www.ncbi.nlm.nih.gov/pubmed/25228468 http://dx.doi.org/10.1093/nar/gku835 |