Tls1 regulates splicing of shelterin components to control telomeric heterochromatin assembly and telomere length

Heterochromatin preferentially forms at repetitive DNA elements through RNAi-mediated targeting of histone-modifying enzymes. It was proposed that splicing factors interact with the RNAi machinery or regulate the splicing of repeat transcripts to directly participate in heterochromatin assembly. Her...

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Detalles Bibliográficos
Autores principales: Wang, Jiyong, Tadeo, Xavier, Hou, Haitong, Andrews, Stuart, Moresco, James J., Yates, John R., Nagy, Peter L., Jia, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191416/
https://www.ncbi.nlm.nih.gov/pubmed/25245948
http://dx.doi.org/10.1093/nar/gku842

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