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Nova1 is a master regulator of alternative splicing in pancreatic beta cells

Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human genes but its role in the regulation of pancreatic beta cells, the producers of insulin, remains unknown. Our recently published data indicated that the ‘neuron-specific’ Nov...

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Detalles Bibliográficos
Autores principales: Villate, Olatz, Turatsinze, Jean-Valery, Mascali, Loriana G., Grieco, Fabio A., Nogueira, Tatiane C., Cunha, Daniel A., Nardelli, Tarlliza R., Sammeth, Michael, Salunkhe, Vishal A., Esguerra, Jonathan L. S., Eliasson, Lena, Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191425/
https://www.ncbi.nlm.nih.gov/pubmed/25249621
http://dx.doi.org/10.1093/nar/gku861