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FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response

Human single-strand (ss) DNA binding proteins 1 (hSSB1) has been shown to participate in DNA damage response and maintenance of genome stability by regulating the initiation of ATM-dependent signaling. ATM phosphorylates hSSB1 and prevents hSSB1 from ubiquitin-proteasome-mediated degradation. Howeve...

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Detalles Bibliográficos
Autores principales:	Chen, Zhi-Wei, Liu, Bin, Tang, Nai-Wang, Xu, Yun-Hua, Ye, Xiang-Yun, Li, Zi-Ming, Niu, Xiao-Min, Shen, Sheng-Ping, Lu, Shun, Xu, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191430/ https://www.ncbi.nlm.nih.gov/pubmed/25249620 http://dx.doi.org/10.1093/nar/gku876

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