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Tryptophan-Catabolizing Enzymes – Party of Three

Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) are tryptophan-degrading enzymes that have independently evolved to catalyze the first step in tryptophan catabolism via the kynurenine pathway (KP). The depletion of tryptophan and formation of KP metabolites modulates the activ...

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Detalles Bibliográficos
Autores principales:	Ball, Helen J., Jusof, Felicita F., Bakmiwewa, Supun M., Hunt, Nicholas H., Yuasa, Hajime J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191572/ https://www.ncbi.nlm.nih.gov/pubmed/25346733 http://dx.doi.org/10.3389/fimmu.2014.00485

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