Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease

[Image: see text] Seasonal and pandemic influenza outbreaks remain a major human health problem. Inhibition of the endonuclease activity of influenza RNA-dependent RNA polymerase is attractive for the development of new agents for the treatment of influenza infection. Our earlier studies identified...

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Detalles Bibliográficos
Autores principales: Sagong, Hye Yeon, Bauman, Joseph D., Patel, Disha, Das, Kalyan, Arnold, Eddy, LaVoie, Edmond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191602/
https://www.ncbi.nlm.nih.gov/pubmed/25225968
http://dx.doi.org/10.1021/jm500958x

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