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Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

We performed a multistage genome-wide association study (GWAS) including 7,683 individuals with pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome-wide significance: rs6971499 at 7q32.3 (LINC-PINT; per-allele odds ratio [OR] = 0.79; 95% confidence interval [CI] =...

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Detalles Bibliográficos
Autores principales: Wolpin, Brian M., Rizzato, Cosmeri, Kraft, Peter, Kooperberg, Charles, Petersen, Gloria M., Wang, Zhaoming, Arslan, Alan A., Beane-Freeman, Laura, Bracci, Paige M., Buring, Julie, Canzian, Federico, Duell, Eric J., Gallinger, Steven, Giles, Graham G., Goodman, Gary E., Goodman, Phyllis J., Jacobs, Eric J., Kamineni, Aruna, Klein, Alison P., Kolonel, Laurence N., Kulke, Matthew H., Li, Donghui, Malats, Núria, Olson, Sara H., Risch, Harvey A., Sesso, Howard D., Visvanathan, Kala, White, Emily, Zheng, Wei, Abnet, Christian C., Albanes, Demetrius, Andreotti, Gabriella, Austin, Melissa A., Barfield, Richard, Basso, Daniela, Berndt, Sonja I., Boutron-Ruault, Marie-Christine, Brotzman, Michelle, Büchler, Markus W., Bueno-de-Mesquita, H. Bas, Bugert, Peter, Burdette, Laurie, Campa, Daniele, Caporaso, Neil E., Capurso, Gabriele, Chung, Charles, Cotterchio, Michelle, Costello, Eithne, Elena, Joanne, Funel, Niccola, Gaziano, J. Michael, Giese, Nathalia A., Giovannucci, Edward L., Goggins, Michael, Gorman, Megan J., Gross, Myron, Haiman, Christopher A., Hassan, Manal, Helzlsouer, Kathy J., Henderson, Brian E., Holly, Elizabeth A., Hu, Nan, Hunter, David J., Innocenti, Federico, Jenab, Mazda, Kaaks, Rudolf, Key, Timothy J., Khaw, Kay-Tee, Klein, Eric A., Kogevinas, Manolis, Krogh, Vittorio, Kupcinskas, Juozas, Kurtz, Robert C., LaCroix, Andrea, Landi, Maria T., Landi, Stefano, Le Marchand, Loic, Mambrini, Andrea, Mannisto, Satu, Milne, Roger L., Nakamura, Yusuke, Oberg, Ann L., Owzar, Kouros, Patel, Alpa V., Peeters, Petra H. M., Peters, Ulrike, Pezzilli, Raffaele, Piepoli, Ada, Porta, Miquel, Real, Francisco X., Riboli, Elio, Rothman, Nathaniel, Scarpa, Aldo, Shu, Xiao-Ou, Silverman, Debra T., Soucek, Pavel, Sund, Malin, Talar-Wojnarowska, Renata, Taylor, Philip R., Theodoropoulos, George E., Thornquist, Mark, Tjønneland, Anne, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Vodicka, Pavel, Wactawski-Wende, Jean, Wentzensen, Nicolas, Wu, Chen, Yu, Herbert, Yu, Kai, Zeleniuch-Jacquotte, Anne, Hoover, Robert, Hartge, Patricia, Fuchs, Charles, Chanock, Stephen J., Stolzenberg-Solomon, Rachael S., Amundadottir, Laufey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191666/
https://www.ncbi.nlm.nih.gov/pubmed/25086665
http://dx.doi.org/10.1038/ng.3052

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