Rodent Models and Behavioral Outcomes of Cervical Spinal Cord Injury

Rodent spinal cord injury (SCI) models have been developed to examine functional and physiological deficits after spinal cord injury with the hope that these models will elucidate information about human SCI. Models are needed to examine possible treatments and to understand histopathology after SCI...

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Detalles Bibliográficos
Autores principales: Geissler, Sydney A., Schmidt, Christine E., Schallert, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191831/
https://www.ncbi.nlm.nih.gov/pubmed/25309824
http://dx.doi.org/10.4172/2165-7939.S4-001
Descripción
Sumario:Rodent spinal cord injury (SCI) models have been developed to examine functional and physiological deficits after spinal cord injury with the hope that these models will elucidate information about human SCI. Models are needed to examine possible treatments and to understand histopathology after SCI; however, they should be considered carefully and chosen based on the goals of the study being performed. Contusion, compression, transection, and other models exist and have the potential to reveal important information about SCI that may be related to human SCI and the outcomes of treatment and timing of intervention.

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