Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

Large-scale surveys of single-cell gene expression have the potential to reveal rare cell populations and lineage relationships, but require efficient methods for cell capture and mRNA sequencing(1–4). Although cellular barcoding strategies allow parallel sequencing of single cells at ultra-low dept...

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Detalles Bibliográficos
Autores principales: Pollen, Alex A, Nowakowski, Tomasz J, Shuga, Joe, Wang, Xiaohui, Leyrat, Anne A, Lui, Jan H, Li, Nianzhen, Szpankowski, Lukasz, Fowler, Brian, Chen, Peilin, Ramalingam, Naveen, Sun, Gang, Thu, Myo, Norris, Michael, Lebofsky, Ronald, Toppani, Dominique, Kemp, Darnell, Wong, Michael, Clerkson, Barry, Jones, Brittnee N, Wu, Shiquan, Knutsson, Lawrence, Alvarado, Beatriz, Wang, Jing, Weaver, Lesley S, May, Andrew P, Jones, Robert C, Unger, Marc A, Kriegstein, Arnold R, West, Jay AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191988/
https://www.ncbi.nlm.nih.gov/pubmed/25086649
http://dx.doi.org/10.1038/nbt.2967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191988/
https://www.ncbi.nlm.nih.gov/pubmed/25086649
http://dx.doi.org/10.1038/nbt.2967

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