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The clinical response to vemurafenib in a patient with a rare BRAF(V600DK601del) mutation-positive melanoma

BACKGROUND: Mutations in the activation segment of the v-raf murine sarcoma viral oncogene homolog B (BRAF) gene are present in approximately 50% of melanomas. The selective BRAF inhibitor vemurafenib has demonstrated significant clinical benefits in patients with melanomas harboring the most common...

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Detalles Bibliográficos
Autores principales:	Trudel, Stéphanie, Odolczyk, Norbert, Dremaux, Julie, Toffin, Jérôme, Regnier, Aline, Sevestre, Henri, Zielenkiewicz, Piotr, Arnault, Jean-Philippe, Gubler, Brigitte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192296/ https://www.ncbi.nlm.nih.gov/pubmed/25265970 http://dx.doi.org/10.1186/1471-2407-14-727

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