Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland

Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and desc...

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Autores principales: Roycroft, Emma, Mac Aogáin, Micheál, O’Toole, Ronan F., Fitzgibbon, Margaret, Rogers, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192383/
https://www.ncbi.nlm.nih.gov/pubmed/25301651
http://dx.doi.org/10.1128/genomeA.01002-14
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author Roycroft, Emma
Mac Aogáin, Micheál
O’Toole, Ronan F.
Fitzgibbon, Margaret
Rogers, Thomas R.
author_facet Roycroft, Emma
Mac Aogáin, Micheál
O’Toole, Ronan F.
Fitzgibbon, Margaret
Rogers, Thomas R.
author_sort Roycroft, Emma
collection PubMed
description Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and describe a number of single-nucleotide variations that correlate with its XDR phenotype.
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spelling pubmed-41923832014-10-12 Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland Roycroft, Emma Mac Aogáin, Micheál O’Toole, Ronan F. Fitzgibbon, Margaret Rogers, Thomas R. Genome Announc Prokaryotes Extensive drug resistance is an emerging threat to the control of tuberculosis (TB) worldwide, even in countries with low TB incidence. We report the draft whole-genome sequence of the first reported extensively drug-resistant TB (XDR-TB) strain isolated in Ireland (a low-incidence setting) and describe a number of single-nucleotide variations that correlate with its XDR phenotype. American Society for Microbiology 2014-10-09 /pmc/articles/PMC4192383/ /pubmed/25301651 http://dx.doi.org/10.1128/genomeA.01002-14 Text en Copyright © 2014 Roycroft et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Roycroft, Emma
Mac Aogáin, Micheál
O’Toole, Ronan F.
Fitzgibbon, Margaret
Rogers, Thomas R.
Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title_full Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title_fullStr Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title_full_unstemmed Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title_short Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
title_sort draft genome sequence of the first isolate of extensively drug-resistant mycobacterium tuberculosis in ireland
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192383/
https://www.ncbi.nlm.nih.gov/pubmed/25301651
http://dx.doi.org/10.1128/genomeA.01002-14
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