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Prevalence of oral anticoagulation in atrial fibrillation

OBJECTIVES: Atrial fibrillation is the most common sustained arrhythmia and is associated with poor outcomes, including stroke. The ability of anticoagulation therapy to reduce the risk of stroke has been well established; however, the prevalence of anticoagulation therapy use in the Public Health S...

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Autores principales: Bartholomay, Eduardo, Polli, Ismael, Borges, Anibal Pires, Kalil, Carlos, Arroque, André, Kohler, Ilmar, Danzmann, Luiz Cláudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192404/
https://www.ncbi.nlm.nih.gov/pubmed/25318093
http://dx.doi.org/10.6061/clinics/2014(09)07
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author Bartholomay, Eduardo
Polli, Ismael
Borges, Anibal Pires
Kalil, Carlos
Arroque, André
Kohler, Ilmar
Danzmann, Luiz Cláudio
author_facet Bartholomay, Eduardo
Polli, Ismael
Borges, Anibal Pires
Kalil, Carlos
Arroque, André
Kohler, Ilmar
Danzmann, Luiz Cláudio
author_sort Bartholomay, Eduardo
collection PubMed
description OBJECTIVES: Atrial fibrillation is the most common sustained arrhythmia and is associated with poor outcomes, including stroke. The ability of anticoagulation therapy to reduce the risk of stroke has been well established; however, the prevalence of anticoagulation therapy use in the Public Health System is unknown. The aim of this study is to evaluate both the prevalence of anticoagulation therapy among patients with atrial fibrillation and the indications for the treatment. METHODS: In this cross-sectional study, we included consecutive patients who had atrial fibrillation documented by an electrocardiogram performed between September 2011 and March 2012 at a university hospital of the Public Health System. The variables analyzed included the risk of a thromboembolic event and/or bleeding, the use of antiplatelet or anticoagulation therapy, the location where the electrocardiogram report was initially reviewed and the specialty of the physician who initially reviewed it. RESULTS: We included 162 patients (mean age 68.9 years, 56% men). Hypertension (90.1%), heart failure (53.4%) and stroke (38.9%) were the most prevalent diseases found. Only 50.6% of the patients knew that they had atrial fibrillation. Regarding the use of therapy, only 37.6% of patients classified as high risk according to the CHADS2 scores and 35.5% according to the CHA2DS2VASc used oral anticoagulation. A presumptive diagnosis of heart failure and the fact that the electrocardiogram was evaluated by a cardiologist were the only independent predictors of the use of anticoagulants. CONCLUSIONS: Our study found a low prevalence of oral anticoagulation therapy among patients with atrial fibrillation and an indication for stroke prophylaxis for the use of this therapy, including among those with high CHADS2 and CHA2DS2VASc scores.
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spelling pubmed-41924042014-10-10 Prevalence of oral anticoagulation in atrial fibrillation Bartholomay, Eduardo Polli, Ismael Borges, Anibal Pires Kalil, Carlos Arroque, André Kohler, Ilmar Danzmann, Luiz Cláudio Clinics (Sao Paulo) Clinical Science OBJECTIVES: Atrial fibrillation is the most common sustained arrhythmia and is associated with poor outcomes, including stroke. The ability of anticoagulation therapy to reduce the risk of stroke has been well established; however, the prevalence of anticoagulation therapy use in the Public Health System is unknown. The aim of this study is to evaluate both the prevalence of anticoagulation therapy among patients with atrial fibrillation and the indications for the treatment. METHODS: In this cross-sectional study, we included consecutive patients who had atrial fibrillation documented by an electrocardiogram performed between September 2011 and March 2012 at a university hospital of the Public Health System. The variables analyzed included the risk of a thromboembolic event and/or bleeding, the use of antiplatelet or anticoagulation therapy, the location where the electrocardiogram report was initially reviewed and the specialty of the physician who initially reviewed it. RESULTS: We included 162 patients (mean age 68.9 years, 56% men). Hypertension (90.1%), heart failure (53.4%) and stroke (38.9%) were the most prevalent diseases found. Only 50.6% of the patients knew that they had atrial fibrillation. Regarding the use of therapy, only 37.6% of patients classified as high risk according to the CHADS2 scores and 35.5% according to the CHA2DS2VASc used oral anticoagulation. A presumptive diagnosis of heart failure and the fact that the electrocardiogram was evaluated by a cardiologist were the only independent predictors of the use of anticoagulants. CONCLUSIONS: Our study found a low prevalence of oral anticoagulation therapy among patients with atrial fibrillation and an indication for stroke prophylaxis for the use of this therapy, including among those with high CHADS2 and CHA2DS2VASc scores. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2014-09 /pmc/articles/PMC4192404/ /pubmed/25318093 http://dx.doi.org/10.6061/clinics/2014(09)07 Text en Copyright © 2014 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Science
Bartholomay, Eduardo
Polli, Ismael
Borges, Anibal Pires
Kalil, Carlos
Arroque, André
Kohler, Ilmar
Danzmann, Luiz Cláudio
Prevalence of oral anticoagulation in atrial fibrillation
title Prevalence of oral anticoagulation in atrial fibrillation
title_full Prevalence of oral anticoagulation in atrial fibrillation
title_fullStr Prevalence of oral anticoagulation in atrial fibrillation
title_full_unstemmed Prevalence of oral anticoagulation in atrial fibrillation
title_short Prevalence of oral anticoagulation in atrial fibrillation
title_sort prevalence of oral anticoagulation in atrial fibrillation
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192404/
https://www.ncbi.nlm.nih.gov/pubmed/25318093
http://dx.doi.org/10.6061/clinics/2014(09)07
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