Cargando…
The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography
BACKGROUND: The purpose of this study was to evaluate whether performing an assessment of myocardial deformation using speckle tracking imaging during the recovery period after dobutamine stress echocardiography (DSE) allows detection of significant coronary artery disease (CAD) in patients with che...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Echocardiography
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192410/ https://www.ncbi.nlm.nih.gov/pubmed/25309689 http://dx.doi.org/10.4250/jcu.2014.22.3.127 |
_version_ | 1782338779609038848 |
---|---|
author | Hwang, Hui-Jeong Lee, Hyae-Min Yang, In-Ho Lee, Jung Lok Pak, Hyun Young Park, Chang-Bum Jin, Eun-Sun Cho, Jin-Man Kim, Chong-Jin Sohn, Il Suk |
author_facet | Hwang, Hui-Jeong Lee, Hyae-Min Yang, In-Ho Lee, Jung Lok Pak, Hyun Young Park, Chang-Bum Jin, Eun-Sun Cho, Jin-Man Kim, Chong-Jin Sohn, Il Suk |
author_sort | Hwang, Hui-Jeong |
collection | PubMed |
description | BACKGROUND: The purpose of this study was to evaluate whether performing an assessment of myocardial deformation using speckle tracking imaging during the recovery period after dobutamine stress echocardiography (DSE) allows detection of significant coronary artery disease (CAD) in patients with chest discomfort. METHODS: DSE and coronary angiography were performed in 44 patients with chest discomfort. The mean global longitudinal peak systolic strain (GLS) was measured at rest, at low stress (dobutamine infusion rate of 10 µg/kg/min) and at recovery (5 min after cessation of dobutamine infusion) of DSE using automated function imaging with apical views. Fractional flow reserve (FFR) was also performed in patients with intermediate coronary stenosis. CAD was defined as having a ≥ 70% diameter stenosis on coronary angiography or as having a FFR < 0.8. Patients were divided two groups based on the absence or presence of CAD [CAD (-) group vs. CAD (+) group]. RESULTS: There were no significant differences in the clinical characteristics and results of conventional echocardiography between the two groups. GLS at recovery was lower in the CAD (+) group than in the CAD (-) group (-18.0 ± 3.4% vs. -21.0 ± 1.9%, p = 0.003). The optimal cutoff of GLS at recovery for detection of CAD was -19% (sensitivity of 70.6%, specificity of 83.3%). CONCLUSION: Assessment of GLS at recovery of DSE is a reliable and objective method for detection of CAD. This finding may suggest that systolic myocardial stunning remains even after recovery of wall motion abnormalities in patients with CAD. |
format | Online Article Text |
id | pubmed-4192410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Korean Society of Echocardiography |
record_format | MEDLINE/PubMed |
spelling | pubmed-41924102014-10-10 The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography Hwang, Hui-Jeong Lee, Hyae-Min Yang, In-Ho Lee, Jung Lok Pak, Hyun Young Park, Chang-Bum Jin, Eun-Sun Cho, Jin-Man Kim, Chong-Jin Sohn, Il Suk J Cardiovasc Ultrasound Original Article BACKGROUND: The purpose of this study was to evaluate whether performing an assessment of myocardial deformation using speckle tracking imaging during the recovery period after dobutamine stress echocardiography (DSE) allows detection of significant coronary artery disease (CAD) in patients with chest discomfort. METHODS: DSE and coronary angiography were performed in 44 patients with chest discomfort. The mean global longitudinal peak systolic strain (GLS) was measured at rest, at low stress (dobutamine infusion rate of 10 µg/kg/min) and at recovery (5 min after cessation of dobutamine infusion) of DSE using automated function imaging with apical views. Fractional flow reserve (FFR) was also performed in patients with intermediate coronary stenosis. CAD was defined as having a ≥ 70% diameter stenosis on coronary angiography or as having a FFR < 0.8. Patients were divided two groups based on the absence or presence of CAD [CAD (-) group vs. CAD (+) group]. RESULTS: There were no significant differences in the clinical characteristics and results of conventional echocardiography between the two groups. GLS at recovery was lower in the CAD (+) group than in the CAD (-) group (-18.0 ± 3.4% vs. -21.0 ± 1.9%, p = 0.003). The optimal cutoff of GLS at recovery for detection of CAD was -19% (sensitivity of 70.6%, specificity of 83.3%). CONCLUSION: Assessment of GLS at recovery of DSE is a reliable and objective method for detection of CAD. This finding may suggest that systolic myocardial stunning remains even after recovery of wall motion abnormalities in patients with CAD. Korean Society of Echocardiography 2014-09 2014-09-29 /pmc/articles/PMC4192410/ /pubmed/25309689 http://dx.doi.org/10.4250/jcu.2014.22.3.127 Text en Copyright © 2014 Korean Society of Echocardiography http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hwang, Hui-Jeong Lee, Hyae-Min Yang, In-Ho Lee, Jung Lok Pak, Hyun Young Park, Chang-Bum Jin, Eun-Sun Cho, Jin-Man Kim, Chong-Jin Sohn, Il Suk The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title | The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title_full | The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title_fullStr | The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title_full_unstemmed | The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title_short | The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography |
title_sort | value of assessing myocardial deformation at recovery after dobutamine stress echocardiography |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192410/ https://www.ncbi.nlm.nih.gov/pubmed/25309689 http://dx.doi.org/10.4250/jcu.2014.22.3.127 |
work_keys_str_mv | AT hwanghuijeong thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT leehyaemin thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT yanginho thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT leejunglok thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT pakhyunyoung thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT parkchangbum thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT jineunsun thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT chojinman thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT kimchongjin thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT sohnilsuk thevalueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT hwanghuijeong valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT leehyaemin valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT yanginho valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT leejunglok valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT pakhyunyoung valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT parkchangbum valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT jineunsun valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT chojinman valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT kimchongjin valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography AT sohnilsuk valueofassessingmyocardialdeformationatrecoveryafterdobutaminestressechocardiography |