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Mutational profiling of kinases in glioblastoma
BACKGROUND: Glioblastoma is a highly malignant brain tumor for which no cure is available. To identify new therapeutic targets, we performed a mutation analysis of kinase genes in glioblastoma. METHODS: Database mining and a literature search identified 76 kinases that have been found to be mutated...
Autores principales: | Bleeker, Fonnet E, Lamba, Simona, Zanon, Carlo, Molenaar, Remco J, Hulsebos, Theo JM, Troost, Dirk, van Tilborg, Angela A, Vandertop, W Peter, Leenstra, Sieger, van Noorden, Cornelis JF, Bardelli, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192443/ https://www.ncbi.nlm.nih.gov/pubmed/25256166 http://dx.doi.org/10.1186/1471-2407-14-718 |
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