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Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis

The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associat...

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Detalles Bibliográficos
Autores principales: Segers, Filip M., Verdam, Froukje J., de Jonge, Charlotte, Boonen, Bas, Driessen, Ann, Shiri-Sverdlov, Ronit, Bouvy, Nicole D., Greve, Jan Willem M., Buurman, Wim A., Rensen, Sander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192551/
https://www.ncbi.nlm.nih.gov/pubmed/25299043
http://dx.doi.org/10.1371/journal.pone.0110053

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