Cargando…

High Resolution Magnetic Resonance Imaging for Characterization of the Neuroligin-3 Knock-in Mouse Model Associated with Autism Spectrum Disorder

Autism spectrum disorders (ASD) comprise an etiologically heterogeneous set of neurodevelopmental disorders. Neuroligin-3 (NL-3) is a cell adhesion protein that mediates synapse development and has been implicated in ASD. We performed ex-vivo high resolution magnetic resonance imaging (MRI), includi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Manoj, Duda, Jeffery T., Hwang, Wei-Ting, Kenworthy, Charles, Ittyerah, Ranjit, Pickup, Stephen, Brodkin, Edward S., Gee, James C., Abel, Ted, Poptani, Harish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192590/ https://www.ncbi.nlm.nih.gov/pubmed/25299583 http://dx.doi.org/10.1371/journal.pone.0109872

Ejemplares similares

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
por: Guneykaya, Dilansu, et al.
Publicado: (2023)

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
por: Zhang, Zhenzhen, et al.
Publicado: (2022)

Reduced inhibitory gate in the barrel cortex of Neuroligin3(R451C) knock‐in mice, an animal model of autism spectrum disorders
por: Cellot, Giada, et al.
Publicado: (2014)

Developmental regulation of GABAergic signalling in the hippocampus of neuroligin 3 R451C knock-in mice: an animal model of Autism
por: Pizzarelli, Rocco, et al.
Publicado: (2013)

Association between Neuroligin-1 polymorphism and plasma glutamine levels in individuals with autism spectrum disorder
por: Lee, In-Hee, et al.
Publicado: (2023)

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice
por: Muellerleile, Julia, et al.
Publicado: (2023)

Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder
por: Steinberg, Karyn Meltz, et al.
Publicado: (2012)

The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis
por: Fujita-Jimbo, Eriko, et al.
Publicado: (2015)

Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
por: Liu, Xing, et al.
Publicado: (2022)

Functional significance of rare neuroligin 1 variants found in autism
por: Nakanishi, Moe, et al.
Publicado: (2017)

In vivo Magnetic Resonance Imaging of Tumor Protease Activity
por: Haris, Mohammad, et al.
Publicado: (2014)

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort
por: Landini, Martina, et al.
Publicado: (2016)

Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
por: Silverman, Jill L., et al.
Publicado: (2022)

PT682. A novel mutation associated autism in Neuroligin1
por: Nakanishi, Moe, et al.
Publicado: (2016)

Correction: Functional significance of rare neuroligin 1 variants found in autism
por: Nakanishi, Moe, et al.
Publicado: (2017)

Genetic Analysis of Neuroligin 4Y Gene in Autism Population of India
por: Hegde, Rajat, et al.
Publicado: (2021)

The distribution of neuroligin4, an autism-related postsynaptic molecule, in the human brain
por: Toya, Akie, et al.
Publicado: (2023)

Neuroligin 3 R451C mutation alters electroencephalography spectral activity in an animal model of autism spectrum disorders
por: Liu, Jackie J., et al.
Publicado: (2017)

Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction
por: Uchigashima, Motokazu, et al.
Publicado: (2021)

Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism
por: Modi, Brijesh, et al.
Publicado: (2019)

Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development
por: Pettem, Katherine L., et al.
Publicado: (2013)

Genetic analysis of the postsynaptic transmembrane X-linked neuroligin 3 gene in autism
por: Hegde, Rajat, et al.
Publicado: (2021)

An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum
por: Lai, Esther Suk King, et al.
Publicado: (2021)

Identification of Four Novel Synonymous Substitutions in the X-Linked Genes Neuroligin 3 and Neuroligin 4X in Japanese Patients with Autistic Spectrum Disorder
por: Yanagi, Kumiko, et al.
Publicado: (2012)

Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking
por: Chanda, Soham, et al.
Publicado: (2015)

Abnormal Social Interactions in a Drosophila Mutant of an Autism Candidate Gene: Neuroligin 3
por: Yost, Ryley T., et al.
Publicado: (2020)

Linking spatial gene expression patterns to sex-specific brain structural changes on a mouse model of 16p11.2 hemideletion
por: Kumar, Vinod Jangir, et al.
Publicado: (2018)

Contrasting Views of Autism Spectrum Traits in Adults, Especially in Self-Reports vs. Informant-Reports for Women High in Autism Spectrum Traits
por: Taylor, Sara C., et al.
Publicado: (2022)

Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms
por: Yumoto, Takafumi, et al.
Publicado: (2020)

Altered Caecal Neuroimmune Interactions in the Neuroligin-3(R451C) Mouse Model of Autism
por: Sharna, Samiha Sayed, et al.
Publicado: (2020)

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents
por: Maxeiner, Stephan, et al.
Publicado: (2020)

Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size
por: Gatford, Nicholas J F, et al.
Publicado: (2021)

A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice
por: Burrows, Emma L., et al.
Publicado: (2015)

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism
por: Hammer, Matthieu, et al.
Publicado: (2015)

Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene
por: Medina, Matías A., et al.
Publicado: (2018)

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses
por: Zhang, Bo, et al.
Publicado: (2018)

Gastrointestinal dysfunction in patients and mice expressing the autism‐associated R451C mutation in neuroligin‐3
por: Hosie, Suzanne, et al.
Publicado: (2019)

Social Isolation Alters Social and Mating Behavior in the R451C Neuroligin Mouse Model of Autism
por: Burrows, E. L., et al.
Publicado: (2017)

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort
por: Yu, Jindan, et al.
Publicado: (2011)

Melatonin ameliorates sleep–wake disturbances and autism‐like behaviors in the Ctnnd2 knock out mouse model of autism spectrum disorders
por: Xu, Man, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ccc2n17kk8lg6viib64kub9769