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Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages

Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. The underlying molecular mechanisms involved remain largely unknown. In this study, we assessed ep...

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Detalles Bibliográficos
Autores principales: Marr, Alexandra K., MacIsaac, Julia L., Jiang, Ruiwei, Airo, Adriana M., Kobor, Michael S., McMaster, W. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192605/
https://www.ncbi.nlm.nih.gov/pubmed/25299267
http://dx.doi.org/10.1371/journal.ppat.1004419