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Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages
Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. The underlying molecular mechanisms involved remain largely unknown. In this study, we assessed ep...
Autores principales: | Marr, Alexandra K., MacIsaac, Julia L., Jiang, Ruiwei, Airo, Adriana M., Kobor, Michael S., McMaster, W. Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192605/ https://www.ncbi.nlm.nih.gov/pubmed/25299267 http://dx.doi.org/10.1371/journal.ppat.1004419 |
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