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Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model
BACKGROUND: It has been recognized that a defect in klotho gene expression accelerates the degeneration of multiple age-sensitive traits. Accumulating evidence indicates that aging is associated with declines in cognitive function and the activity of growth hormone (GH)/insulin-like growth factor-1...
Autores principales: | Park, Seok Joo, Chung, Yoon Hee, Lee, Jeong Hyun, Dang, Duy-Khanh, Nam, Yunsung, Jeong, Ji Hoon, Kim, Yong Sun, Nabeshima, Toshitaka, Shin, Eun-Joo, Kim, Hyoung-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192803/ https://www.ncbi.nlm.nih.gov/pubmed/25309793 http://dx.doi.org/10.3803/EnM.2014.29.3.336 |
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