Cargando…

Ghrelin Inhibits Oligodendrocyte Cell Death by Attenuating Microglial Activation

BACKGROUND: Recently, we reported the antiapoptotic effect of ghrelin in spinal cord injury-induced apoptotic cell death of oligodendrocytes. However, how ghrelin inhibits oligodendrocytes apoptosis, is still unknown. Therefore, in the present study, we examined whether ghrelin inhibits microglia ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jee Youn, Yune, Tae Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192814/ https://www.ncbi.nlm.nih.gov/pubmed/25309797 http://dx.doi.org/10.3803/EnM.2014.29.3.371

Ejemplares similares

Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation
por: Lee, Sungyoub, et al.
Publicado: (2012)

Ginseng Extracts, GS-KG9 and GS-E3D, Prevent Blood–Brain Barrier Disruption and Thereby Inhibit Apoptotic Cell Death of Hippocampal Neurons in Streptozotocin-Induced Diabetic Rats
por: Lee, Jee Youn, et al.
Publicado: (2020)

Ethanol Extract of Bupleurum falcatum Improves Functional Recovery by Inhibiting Matrix Metalloproteinases-2 and -9 Activation and Inflammation after Spinal Cord Injury
por: Lee, Jee Youn, et al.
Publicado: (2010)

Microglial ASD-related genes are involved in oligodendrocyte differentiation
por: Takanezawa, Yuta, et al.
Publicado: (2021)

Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice
por: Yuan, Lin, et al.
Publicado: (2016)

Quantification of microglial contact and engulfment of oligodendrocyte progenitor cells in the rodent brain
por: Nemes-Baran, Ashley D., et al.
Publicado: (2021)

Levo-Tetrahydropalmatine Attenuates Bone Cancer Pain by Inhibiting Microglial Cells Activation
por: Zhang, Mao-yin, et al.
Publicado: (2015)

Fractalkine-Dependent Microglial Pruning of Viable Oligodendrocyte Progenitor Cells Regulates Myelination
por: Nemes-Baran, Ashley D., et al.
Publicado: (2020)

Erratum: Lee et al. Ginseng Extracts, GS-KG9 and GS-E3D, Prevent Blood–Brain Barrier Disruption and Thereby Inhibit Apoptotic Cell Death of Hippocampal Neurons in Streptozotocin-Induced Diabetic Rats. Nutrients 2020, 12, 2383
por: Lee, Jee Youn, et al.
Publicado: (2021)

Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics
por: N Mohammadi, Ehsan, et al.
Publicado: (2020)

Ghrelin Represses Thymic Stromal Lymphopoietin Gene Expression through Activation of Glucocorticoid Receptor and Protein Kinase C Delta in Inflamed Skin Keratinocytes
por: Jeong, Hayan, et al.
Publicado: (2022)

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
por: Baldanzi, Gianluca, et al.
Publicado: (2002)

Circulating Ghrelin Levels and Obestatin/Ghrelin Ratio as a Marker of Activity in Ulcerative Colitis
por: Jung, Ja Young, et al.
Publicado: (2015)

A New Neolignan Derivative, Balanophonin Isolated from Firmiana simplex Delays the Progress of Neuronal Cell Death by Inhibiting Microglial Activation
por: Lim, Soo Young, et al.
Publicado: (2017)

Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation
por: Nam, Kyong Nyon, et al.
Publicado: (2013)

Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss
por: Song, Dae-Yong, et al.
Publicado: (2013)

Deficiency of Microglial Autophagy Increases the Density of Oligodendrocytes and Susceptibility to Severe Forms of Seizures
por: Alam, Mahabub Maraj, et al.
Publicado: (2021)

Analgesic Effect of Acupuncture Is Mediated via Inhibition of JNK Activation in Astrocytes after Spinal Cord Injury
por: Lee, Jee Y., et al.
Publicado: (2013)

Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress
por: Ślusarczyk, Joanna, et al.
Publicado: (2016)

Vaccinium bracteatum Thunb. Exerts Anti-Inflammatory Activity by Inhibiting NF-κB Activation in BV-2 Microglial Cells
por: Kwon, Seung-Hwan, et al.
Publicado: (2016)

Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway
por: Zhang, Shaoren, et al.
Publicado: (2018)

Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death
por: D'Souza, Sameer D., et al.
Publicado: (1996)

Non-cell autonomous impairment of oligodendrocyte differentiation precedes CNS degeneration in the Zitter rat: Implications of macrophage/microglial activation in the pathogenesis
por: Sakakibara, Shin-ichi, et al.
Publicado: (2008)

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
por: Rojanathammanee, Lalida, et al.
Publicado: (2015)

Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury
por: Song, Shanshan, et al.
Publicado: (2022)

Potentiation of ghrelin signaling attenuates cancer anorexia–cachexia and prolongs survival
por: Fujitsuka, N, et al.
Publicado: (2011)

Neurotransmitter receptors in the life and death of oligodendrocytes
por: Káradóttir, R., et al.
Publicado: (2007)

Retracted: Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress
por: Plasticity, Neural
Publicado: (2018)

Efonidipine Inhibits JNK and NF-κB Pathway to Attenuate Inflammation and Cell Migration Induced by Lipopolysaccharide in Microglial Cells
por: Nguyen, Ngoc Minh, et al.
Publicado: (2022)

Caspase-11 Mediates Oligodendrocyte Cell Death and Pathogenesis of Autoimmune-Mediated Demyelination
por: Hisahara, Shin, et al.
Publicado: (2001)

Ammoxetine attenuates diabetic neuropathic pain through inhibiting microglial activation and neuroinflammation in the spinal cord
por: Zhang, Ting-Ting, et al.
Publicado: (2018)

Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation
por: Zhao, Nanxia, et al.
Publicado: (2020)

Cerebral Ischemic Preconditioning Aggravates Death of Oligodendrocytes
por: Guan, Teng, et al.
Publicado: (2022)

Sinapic Acid Attenuates the Neuroinflammatory Response by Targeting AKT and MAPK in LPS-Activated Microglial Models
por: Huang, Tianqi, et al.
Publicado: (2023)

HDAC2/3 inhibitor MI192 mitigates oligodendrocyte loss and reduces microglial activation upon injury: A potential role of epigenetics
por: Al-Griw, Mohamed A., et al.
Publicado: (2021)

Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway
por: Lee, Jiunn-Tay, et al.
Publicado: (2004)

Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection
por: Norris, Geoffrey T., et al.
Publicado: (2023)

Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor
por: Sherafat, Amin, et al.
Publicado: (2021)

Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection
por: Norris, Geoffrey T., et al.
Publicado: (2023)

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin
por: Kozorosky, Erica M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v5mj0jct4t364dk2nnta6vck22