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Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
Orthology inference and other sequence analyses across multiple genomes typically start by performing exhaustive pairwise sequence comparisons, a process referred to as “all-against-all”. As this process scales quadratically in terms of the number of sequences analysed, this step can become a bottle...
Autores principales: | Wittwer, Lucas D., Piližota, Ivana, Altenhoff, Adrian M., Dessimoz, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193403/ https://www.ncbi.nlm.nih.gov/pubmed/25320677 http://dx.doi.org/10.7717/peerj.607 |
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