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MiR-21 Simultaneously Regulates ERK1 Signaling in HSC Activation and Hepatocyte EMT in Hepatic Fibrosis

BACKGROUND: MicroRNA-21 (miR-21) plays an important role in the pathogenesis and progression of liver fibrosis. Here, we determined the serum and hepatic content of miR-21 in patients with liver cirrhosis and rats with dimethylnitrosamine-induced hepatic cirrhosis and examined the effects of miR-21...

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Detalles Bibliográficos
Autores principales:	Zhao, Juan, Tang, Nan, Wu, Kaiming, Dai, Weiping, Ye, Changhong, Shi, Jian, Zhang, Junping, Ning, Beifang, Zeng, Xin, Lin, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193742/ https://www.ncbi.nlm.nih.gov/pubmed/25303175 http://dx.doi.org/10.1371/journal.pone.0108005

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