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Serum Response Factor Accelerates the High Glucose-Induced Epithelial-to-Mesenchymal Transition (EMT) via Snail Signaling in Human Peritoneal Mesothelial Cells

BACKGROUND: Epithelial-to-Mesenchymal Transition (EMT) induced by glucose in human peritoneal mesothelial cells (HPMCs) is a major cause of peritoneal membrane (PM) fibrosis and dysfunction. METHODS: To investigate serum response factor (SRF) impacts on EMT-derived fibrosis in PM, we isolated HPMCs...

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Detalles Bibliográficos
Autores principales:	He, Lijie, Lou, Weijuan, Ji, Lihua, Liang, Wei, Zhou, Meilan, Xu, Guoshang, Zhao, Lijuan, Huang, Chen, Li, Rong, Wang, Hanmin, Chen, Xiangmei, Sun, Shiren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193747/ https://www.ncbi.nlm.nih.gov/pubmed/25303231 http://dx.doi.org/10.1371/journal.pone.0108593

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