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A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2
We recently described a novel receptor cross-talk mechanism in neutrophils, unique in that the signals generated by the PAF receptor (PAFR) and the ATP receptor (P2Y(2)R) transfer formyl peptide receptor 1 (FPR1) from a desensitized (non-signaling) state back to an actively signaling state (Forsman...
Autores principales: | Gabl, Michael, Winther, Malene, Skovbakke, Sarah Line, Bylund, Johan, Dahlgren, Claes, Forsman, Huamei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193777/ https://www.ncbi.nlm.nih.gov/pubmed/25303226 http://dx.doi.org/10.1371/journal.pone.0109516 |
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