Clearance of Human IgG1-Sensitised Red Blood Cells In Vivo in Humans Relates to the In Vitro Properties of Antibodies from Alternative Cell Lines

We previously produced a recombinant version of the human anti-RhD antibody Fog-1 in the rat myeloma cell line, YB2/0. When human, autologous RhD-positive red blood cells (RBC) were sensitised with this IgG1 antibody and re-injected, they were cleared much more rapidly from the circulation than had...

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Detalles Bibliográficos
Autores principales: Armour, Kathryn L., Smith, Cheryl S., Ip, Natasha C. Y., Ellison, Cara J., Kirton, Christopher M., Wilkes, Anthony M., Williamson, Lorna M., Clark, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193810/
https://www.ncbi.nlm.nih.gov/pubmed/25302805
http://dx.doi.org/10.1371/journal.pone.0109463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193810/
https://www.ncbi.nlm.nih.gov/pubmed/25302805
http://dx.doi.org/10.1371/journal.pone.0109463

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