Joint Testing of Genotypic and Gene-Environment Interaction Identified Novel Association for BMP4 with Non-Syndromic CL/P in an Asian Population Using Data from an International Cleft Consortium

BACKGROUND: Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common disorder with complex etiology. The Bone Morphogenetic Protein 4 gene (BMP4) has been considered a prime candidate gene with evidence accumulated from animal experimental studies, human linkage studies, as well as...

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Detalles Bibliográficos
Autores principales: Chen, Qianqian, Wang, Hong, Schwender, Holger, Zhang, Tianxiao, Hetmanski, Jacqueline B., Chou, Yah-Huei Wu, Ye, Xiaoqian, Yeow, Vincent, Chong, Samuel S., Zhang, Bo, Jabs, Ethylin Wang, Parker, Margaret M., Scott, Alan F., Beaty, Terri H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193821/
https://www.ncbi.nlm.nih.gov/pubmed/25303326
http://dx.doi.org/10.1371/journal.pone.0109038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193821/
https://www.ncbi.nlm.nih.gov/pubmed/25303326
http://dx.doi.org/10.1371/journal.pone.0109038

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