Obesity Has an Interactive Effect with Genetic Variation in the Activating Transcription Factor 6 Gene on the Risk of Pre-Diabetes in Individuals of Chinese Han Descent

Endoplasmic reticulum (ER) stress is one of the contributing factors to the development of β-cell failure in type 2 diabetes. ER stress response through ATF6 has been shown to play an important role in insulin resistance and pancreatic β-cell function. We investigated whether genetic polymorphisms i...

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Detalles Bibliográficos
Autores principales: Gu, Nan, Ma, Xiaowei, Zhang, Junqing, Dong, Aimei, Jin, Mengmeng, Feng, Nan, Zhang, Hong, Guo, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193822/
https://www.ncbi.nlm.nih.gov/pubmed/25302688
http://dx.doi.org/10.1371/journal.pone.0109805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193822/
https://www.ncbi.nlm.nih.gov/pubmed/25302688
http://dx.doi.org/10.1371/journal.pone.0109805

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