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Obesity Has an Interactive Effect with Genetic Variation in the Activating Transcription Factor 6 Gene on the Risk of Pre-Diabetes in Individuals of Chinese Han Descent

Endoplasmic reticulum (ER) stress is one of the contributing factors to the development of β-cell failure in type 2 diabetes. ER stress response through ATF6 has been shown to play an important role in insulin resistance and pancreatic β-cell function. We investigated whether genetic polymorphisms i...

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Detalles Bibliográficos
Autores principales:	Gu, Nan, Ma, Xiaowei, Zhang, Junqing, Dong, Aimei, Jin, Mengmeng, Feng, Nan, Zhang, Hong, Guo, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193822/ https://www.ncbi.nlm.nih.gov/pubmed/25302688 http://dx.doi.org/10.1371/journal.pone.0109805

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