Regulation of the AbrA1/A2 Two-Component System in Streptomyces coelicolor and the Potential of Its Deletion Strain as a Heterologous Host for Antibiotic Production

The Two-Component System (TCS) AbrA1/A2 from Streptomyces coelicolor M145 is a negative regulator of antibiotic production and morphological differentiation. In this work we show that it is able to auto-regulate its expression, exerting a positive induction of its own operon promoter, and that its a...

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Detalles Bibliográficos
Autores principales: Rico, Sergio, Yepes, Ana, Rodríguez, Héctor, Santamaría, Jorge, Antoraz, Sergio, Krause, Eva M., Díaz, Margarita, Santamaría, Ramón I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193843/
https://www.ncbi.nlm.nih.gov/pubmed/25303210
http://dx.doi.org/10.1371/journal.pone.0109844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193843/
https://www.ncbi.nlm.nih.gov/pubmed/25303210
http://dx.doi.org/10.1371/journal.pone.0109844

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