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A Lower Degree of PBMC L1 Methylation in Women with Lower Folate Status May Explain the MTHFR C677T Polymorphism Associated Higher Risk of CIN in the US Post Folic Acid Fortification Era

BACKGROUND: Studies in populations unexposed to folic acid (FA) fortification have demonstrated that MTHFR C677T polymorphism is associated with increased risk of higher grades of cervical intraepithelial neoplasia (CIN 2+). However, it is unknown whether exposure to higher folate as a result of the...

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Detalles Bibliográficos
Autores principales:	Badiga, Suguna, Johanning, Gary L., Macaluso, Maurizio, Azuero, Andres, Chambers, Michelle M., Siddiqui, Nuzhat R., Piyathilake, Chandrika J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193871/ https://www.ncbi.nlm.nih.gov/pubmed/25302494 http://dx.doi.org/10.1371/journal.pone.0110093

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