Opioid-Induced Mitogen-Activated Protein Kinase Signaling in Rat Enteric Neurons following Chronic Morphine Treatment

Opioids, acting at μ opioid receptors, are commonly used for pain management. Chronic opioid treatment induces cellular adaptations, which trigger long-term side effects, including constipation mediated by enteric neurons. We tested the hypothesis that chronic opioid treatment induces alterations of...

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Detalles Bibliográficos
Autores principales: Duraffourd, Celine, Kumala, Erica, Anselmi, Laura, Brecha, Nicholas C., Sternini, Catia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193881/
https://www.ncbi.nlm.nih.gov/pubmed/25302800
http://dx.doi.org/10.1371/journal.pone.0110230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193881/
https://www.ncbi.nlm.nih.gov/pubmed/25302800
http://dx.doi.org/10.1371/journal.pone.0110230

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