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Retinal transduction profiles by high-capacity viral vectors

Retinal gene therapy with adeno-associated viral (AAV) vectors is safe and effective in humans. However, the limited cargo capacity of AAV prevents their use for therapy of those inherited retinopathies (IRs) due to mutations in large (>5kb) genes. Viral vectors derived from Adenovirus (Ad), Lent...

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Detalles Bibliográficos
Autores principales:	Puppo, Agostina, Cesi, Giulia, Marrocco, Elena, Piccolo, Pasquale, Jacca, Sarah, Shayakhmetov, Dmitry M., Parks, Robin J., Davidson, Beverly L., Colloca, Stefano, Brunetti-Pierri, Nicola, Ng, Philip, Donofrio, Gaetano, Auricchio, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193889/ https://www.ncbi.nlm.nih.gov/pubmed/24989814 http://dx.doi.org/10.1038/gt.2014.57

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