Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells

BACKGROUND: The GBGT1 gene encodes the globoside alpha-1,3-N-acetylgalactosaminyltransferase 1. This enzyme catalyzes the last step in the multi-step biosynthesis of the Forssman (Fs) antigen, a pentaglycosyl ceramide of the globo series glycosphingolipids. While differential GBGT1 mRNA expression h...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacob, Francis, Hitchins, Megan P, Fedier, André, Brennan, Kevin, Nixdorf, Sheri, Hacker, Neville F, Ward, Robyn, Heinzelmann-Schwarz, Viola A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193910/
https://www.ncbi.nlm.nih.gov/pubmed/25294702
http://dx.doi.org/10.1186/1471-2199-15-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193910/
https://www.ncbi.nlm.nih.gov/pubmed/25294702
http://dx.doi.org/10.1186/1471-2199-15-24

Ejemplares similares