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c-Src drives intestinal regeneration and transformation

The non-receptor tyrosine kinase c-Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and potential activating mutations in up to 20%of th...

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Detalles Bibliográficos
Autores principales:	Cordero, Julia B, Ridgway, Rachel A, Valeri, Nicola, Nixon, Colin, Frame, Margaret C, Muller, William J, Vidal, Marcos, Sansom, Owen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194090/ https://www.ncbi.nlm.nih.gov/pubmed/24788409 http://dx.doi.org/10.1002/embj.201387454

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