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The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma
BACKGROUND: The anti-inflammatory effects of the selective phosphodiesterase (PDE) inhibitors cilostazol (PDE 3), RO 20-1724 (PDE 4) and sildenafil (PDE 5) were examined in a murine model of allergic asthma. These compounds were used alone and in combination to determine any potential synergism, wit...
Autores principales: | Clayton, Robert A, Dick, Colin AJ, Mackenzie, Alison, Nagasawa, Michiaki, Galbraith, Deirdre, Hastings, Stuart F, MacKenzie, Simon J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419478/ https://www.ncbi.nlm.nih.gov/pubmed/15169552 http://dx.doi.org/10.1186/1465-9921-5-4 |
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