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Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam
Clobazam orally dissolving strips were prepared by solvent casting method. A full 3(2) factorial design was applied for optimization using different concentration of film forming polymer and disintegrating agent as independent variable and disintegration time, % cumulative drug release, and tensile...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195261/ https://www.ncbi.nlm.nih.gov/pubmed/25328709 http://dx.doi.org/10.1155/2014/392783 |