Cargando…

Optogenetics reveals a role for accumbal medium spiny neurons expressing dopamine D2 receptors in cocaine-induced behavioral sensitization

Long-lasting, drug-induced adaptations within the nucleus accumbens (NAc) have been proposed to contribute to drug-mediated addictive behaviors. Here we have used an optogenetic approach to examine the role of NAc medium spiny neurons (MSNs) expressing dopamine D2 receptors (D2Rs) in cocaine-induced...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Shelly Sooyun, Kang, Byeong Jun, Wen, Lei, Lee, Hyo Jin, Sim, Hye-ri, Kim, Tae Hyong, Yoon, Sehyoun, Yoon, Bong-June, Augustine, George J., Baik, Ja-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195370/ https://www.ncbi.nlm.nih.gov/pubmed/25352792 http://dx.doi.org/10.3389/fnbeh.2014.00336

Ejemplares similares

The Role of Accumbal Hypoactivity in Cocaine Addiction.
por: Peoples, L. L., et al.
Publicado: (2007)

HIV-1 and cocaine disrupt dopamine reuptake and medium spiny neurons in female rat striatum
por: Javadi-Paydar, Mehrak, et al.
Publicado: (2017)

Dopamine D2 receptor-mediated circuit from the central amygdala to the bed nucleus of the stria terminalis regulates impulsive behavior
por: Kim, Bokyeong, et al.
Publicado: (2018)

Dynamic dichotomy of accumbal population activity underlies cocaine sensitization
por: van Zessen, Ruud, et al.
Publicado: (2021)

Accumbal Dopamine Release Tracks the Expectation of Dopamine Neuron-Mediated Reinforcement
por: Covey, Dan P., et al.
Publicado: (2019)

Identification of Optogenetically Activated Striatal Medium Spiny Neurons by Npas4 Expression
por: Bepari, Asim K., et al.
Publicado: (2012)

Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference
por: Jerlhag, Elisabet, et al.
Publicado: (2010)

Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning
por: Zanella, Daniele, et al.
Publicado: (2023)

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use
por: Bock, Roland, et al.
Publicado: (2013)

Cocaine-Induced Behavioral Sensitization in Mice: Effects of Microinjection of Dopamine D2 Receptor Antagonist into the Nucleus Accumbens
por: Jung, Eun-Sol, et al.
Publicado: (2013)

Npas4 regulates medium spiny neuron physiology and gates cocaine‐induced hyperlocomotion
por: Lissek, Thomas, et al.
Publicado: (2021)

Concomitant Release of Ventral Tegmental Acetylcholine and Accumbal Dopamine by Ghrelin in Rats
por: Jerlhag, Elisabet, et al.
Publicado: (2012)

Role of Dopamine D2 Receptor in Stress-Induced Myelin Loss
por: Choi, Mi-Hyun, et al.
Publicado: (2017)

The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens
por: Baimel, Corey, et al.
Publicado: (2019)

Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine
por: Phillips, Robert A., et al.
Publicado: (2023)

Opposite Consequences of Tonic and Phasic Increases in Accumbal Dopamine on Alcohol-Seeking Behavior
por: Budygin, Evgeny A., et al.
Publicado: (2020)

Altered Accumbal Dopamine Terminal Dynamics Following Chronic Heroin Self-Administration
por: George, Brianna E., et al.
Publicado: (2022)

Short-Term Consequences of Single Social Defeat on Accumbal Dopamine and Behaviors in Rats
por: Nemets, Vsevolod V., et al.
Publicado: (2022)

Publisher Correction: Role of Dopamine D2 Receptor in Stress-Induced Myelin Loss
por: Choi, Mi-Hyun, et al.
Publicado: (2018)

Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway
por: Kumaresan, Vidhya, et al.
Publicado: (2023)

Changes in Striatal Medium Spiny Neuron Morphology Resulting from Dopamine Depletion Are Reversible
por: Witzig, Victoria Sofie, et al.
Publicado: (2020)

A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction
por: Zhao, Zheng-dong, et al.
Publicado: (2022)

Attenuation of Stimulated Accumbal Dopamine Release by NMDA Is Mediated through Metabotropic Glutamate Receptors
por: Spencer, Felicity S. E., et al.
Publicado: (2023)

Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro
por: Geldwert, Daron, et al.
Publicado: (2006)

PT679. Apathy and striatal dopamine receptor type 2-expressing medium spiny neurons
por: Iku, Tsutsui-Kimura, et al.
Publicado: (2016)

Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens
por: Ma, Yao-Ying, et al.
Publicado: (2013)

Cholinergic interneurons mediate cocaine extinction in male mice through plasticity across medium spiny neuron subtypes
por: Fleming, Weston, et al.
Publicado: (2022)

Noradrenaline-induced release of newly-synthesized accumbal dopamine: differential role of alpha- and beta-adrenoceptors
por: Meyer, Francisca, et al.
Publicado: (2014)

Effects of systemic glycine on accumbal glycine and dopamine levels and ethanol intake in male Wistar rats
por: Olsson, Yasmin, et al.
Publicado: (2020)

Phase-adaptive brain stimulation of striatal D1 medium spiny neurons in dopamine-depleted mice
por: Kim, Youngcho, et al.
Publicado: (2022)

Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine
por: Browne, Caleb J, et al.
Publicado: (2023)

Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity
por: Chen, He, et al.
Publicado: (2022)

Optogenetic inhibition of cocaine seeking in rats
por: Stefanik, Michael T, et al.
Publicado: (2013)

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens
por: Mizuno, Takeo, et al.
Publicado: (2007)

Selective Deletion of PTEN in Dopamine Neurons Leads to Trophic Effects and Adaptation of Striatal Medium Spiny Projecting Neurons
por: Diaz-Ruiz, Oscar, et al.
Publicado: (2009)

Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation
por: Tsutsui-Kimura, Iku, et al.
Publicado: (2017)

Differential Protein Expression in Striatal D1- and D2-Dopamine Receptor-Expressing Medium Spiny Neurons
por: Mansuri, M. Shahid, et al.
Publicado: (2020)

Learning intrinsic excitability in medium spiny neurons
por: Scheler, Gabriele
Publicado: (2014)

A Role for Accumbal Glycine Receptors in Modulation of Dopamine Release by the Glycine Transporter-1 Inhibitor Org25935
por: Lidö, Helga Höifödt, et al.
Publicado: (2011)

The glycine-containing dipeptide leucine-glycine raises accumbal dopamine levels in a subpopulation of rats presenting a lower endogenous dopamine tone
por: Olsson, Yasmin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c7tqblsud4vjobt2a7g3gtcv2l