Early life stress and serotonin transporter gene variation interact to affect the transcription of the glucocorticoid and mineralocorticoid receptors, and the co-chaperone FKBP5, in the adult rat brain

The short allelic variant of the serotonin transporter (5-HTT) promoter-linked polymorphic region (5-HTTLPR) has been associated with the etiology of major depression by interaction with early life stress (ELS). A frequently observed endophenotype in depression is the abnormal regulation of levels o...

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Detalles Bibliográficos
Autores principales: van der Doelen, Rick H. A., Calabrese, Francesca, Guidotti, Gianluigi, Geenen, Bram, Riva, Marco A., Kozicz, Tamás, Homberg, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195371/
https://www.ncbi.nlm.nih.gov/pubmed/25352794
http://dx.doi.org/10.3389/fnbeh.2014.00355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195371/
https://www.ncbi.nlm.nih.gov/pubmed/25352794
http://dx.doi.org/10.3389/fnbeh.2014.00355

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