Cargando…
Early life stress and serotonin transporter gene variation interact to affect the transcription of the glucocorticoid and mineralocorticoid receptors, and the co-chaperone FKBP5, in the adult rat brain
The short allelic variant of the serotonin transporter (5-HTT) promoter-linked polymorphic region (5-HTTLPR) has been associated with the etiology of major depression by interaction with early life stress (ELS). A frequently observed endophenotype in depression is the abnormal regulation of levels o...
Autores principales: | van der Doelen, Rick H. A., Calabrese, Francesca, Guidotti, Gianluigi, Geenen, Bram, Riva, Marco A., Kozicz, Tamás, Homberg, Judith R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195371/ https://www.ncbi.nlm.nih.gov/pubmed/25352794 http://dx.doi.org/10.3389/fnbeh.2014.00355 |
Ejemplares similares
-
Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis
por: van der Doelen, R H A, et al.
Publicado: (2014) -
Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5
por: Hartmann, Jakob, et al.
Publicado: (2021) -
Impaired Fear Extinction Recall in Serotonin Transporter Knockout Rats Is Transiently Alleviated during Adolescence
por: Schipper, Pieter, et al.
Publicado: (2019) -
Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy
por: Baida, Gleb, et al.
Publicado: (2018) -
Altered inflammatory responsiveness in serotonin transporter mutant rats
por: Macchi, Flavia, et al.
Publicado: (2013)