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Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C(∧)N-Chelated and Pyridine Ligands

[Image: see text] We report the synthesis and characterization of eight half-sandwich cyclopentadienyl Ir(III) pyridine complexes of the type [(η(5)-Cp(xph))Ir(phpy)Z]PF(6), in which Cp(xph) = C(5)Me(4)C(6)H(5) (tetramethyl(phenyl)cyclopentadienyl), phpy = 2-phenylpyridine as C(∧)N-chelating ligand,...

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Detalles Bibliográficos
Autores principales: Liu, Zhe, Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J., Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195516/
https://www.ncbi.nlm.nih.gov/pubmed/25328266
http://dx.doi.org/10.1021/om500644f