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Bio-Inspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin
[Image: see text] A new glucose-responsive formulation for self-regulated insulin delivery was constructed by packing insulin, glucose-specific enzymes into pH-sensitive polymersome-based nanovesicles assembled by a diblock copolymer. Glucose can passively transport across the bilayer membrane of th...
Autores principales: | Tai, Wanyi, Mo, Ran, Di, Jin, Subramanian, Vinayak, Gu, Xiao, Buse, John B., Gu, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195518/ https://www.ncbi.nlm.nih.gov/pubmed/25268758 http://dx.doi.org/10.1021/bm500364a |
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