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Cytoskeletal Dependence of Insulin Granule Movement Dynamics in INS-1 Beta-Cells in Response to Glucose

For pancreatic β-cells to secrete insulin in response to elevated blood glucose, insulin granules retained within the subplasmalemmal space must be transported to sites of secretion on the plasma membrane. Using a combination of super-resolution STORM imaging and live cell TIRF microscopy we investi...

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Detalles Bibliográficos
Autores principales:	Heaslip, Aoife T., Nelson, Shane R., Lombardo, Andrew T., Beck Previs, Samantha, Armstrong, Jessica, Warshaw, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195697/ https://www.ncbi.nlm.nih.gov/pubmed/25310693 http://dx.doi.org/10.1371/journal.pone.0109082

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