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Inflammation and MiR-21 Pathways Functionally Interact to Downregulate PDCD4 in Colorectal Cancer
Inflammation plays a direct role in colorectal cancer (CRC) progression; however the molecular mechanisms responsible for this effect are unclear. The inflammation induced cyclooxygenase 2 (COX-2) enzyme required for the production of Prostaglandin E2 (PGE(2)), can promote colorectal cancer by decre...
Autores principales: | Peacock, Oliver, Lee, Andrew C., Cameron, Fraser, Tarbox, Rebecca, Vafadar-Isfahani, Natasha, Tufarelli, Cristina, Lund, Jonathan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195713/ https://www.ncbi.nlm.nih.gov/pubmed/25310697 http://dx.doi.org/10.1371/journal.pone.0110267 |
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