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A Novel 2.5D Culture Platform to Investigate the Role of Stiffness Gradients on Adhesion-Independent Cell Migration

Current studies investigating the role of biophysical cues on cell migration focus on the use of culture platforms with static material parameters. However, migrating cells in vivo often encounter spatial variations in extracellular matrix stiffness. To better understand the effects of stiffness gra...

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Detalles Bibliográficos
Autores principales: Pebworth, Mark-Phillip, Cismas, Sabrina A., Asuri, Prashanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195729/
https://www.ncbi.nlm.nih.gov/pubmed/25310593
http://dx.doi.org/10.1371/journal.pone.0110453