Cargando…

Mapping early fate determination in Lgr5(+) crypt stem cells using a novel Ki67-RFP allele

Cycling Lgr5(+) stem cells fuel the rapid turnover of the adult intestinal epithelium. The existence of quiescent Lgr5(+) cells has been reported, while an alternative quiescent stem cell population is believed to reside at crypt position +4. Here, we generated a novel Ki67(RFP) knock-in allele that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basak, Onur, van de Born, Maaike, Korving, Jeroen, Beumer, Joep, van der Elst, Stefan, van Es, Johan H, Clevers, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195772/ https://www.ncbi.nlm.nih.gov/pubmed/25092767 http://dx.doi.org/10.15252/embj.201488017

Ejemplares similares

RfpA, RfpB, and RfpC are the Master Control Elements of Far-Red Light Photoacclimation (FaRLiP)
por: Zhao, Chi, et al.
Publicado: (2015)

Corrigendum: RfpA, RfpB, and RfpC are the Master Control Elements of Far-Red Light Photoacclimation (FaRLiP)
por: Zhao, Chi, et al.
Publicado: (2019)

Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion
por: Snippert, Hugo J, et al.
Publicado: (2014)

LGR6 marks nephron progenitor cells
por: van Ineveld, Ravian L., et al.
Publicado: (2021)

Ki-67 gene expression
por: Uxa, Sigrid, et al.
Publicado: (2021)

DNA mimics of red fluorescent proteins (RFP) based on G-quadruplex-confined synthetic RFP chromophores
por: Feng, Guangfu, et al.
Publicado: (2017)

Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals
por: Inutsuka, Ayumu, et al.
Publicado: (2022)

Recurrence of Pancreatic Neuroendocrine Tumors and Survival Predicted by Ki67
por: Genç, C. G., et al.
Publicado: (2018)

To Ki or Not to Ki: Re-Evaluating the Use and Potentials of Ki-67 for T Cell Analysis
por: Di Rosa, Francesca, et al.
Publicado: (2021)

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67
por: van Schaik, Tom, et al.
Publicado: (2022)

Enteroendocrine Dynamics – New Tools Reveal Hormonal Plasticity in the Gut
por: Beumer, Joep, et al.
Publicado: (2020)

The Organoid Platform: Promises and Challenges as Tools in the Fight against COVID-19
por: Geurts, Maarten H., et al.
Publicado: (2021)

Colon Crypts of Subjects With Familial Adenomatous Polyposis Show an Increased Number of LGR5+ Ectopic Stem Cells
por: Jennelle, Lucas T., et al.
Publicado: (2021)

Corrigendum: To Ki or Not to Ki: Re-Evaluating the Use and Potentials of Ki-67 for T Cell Analysis
por: Di Rosa, Francesca, et al.
Publicado: (2021)

The intrinsically disorderly story of Ki-67
por: Remnant, Lucy, et al.
Publicado: (2021)

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors
por: van Es, Johan H., et al.
Publicado: (2010)

Profiling proliferative cells and their progeny in damaged murine hearts
por: Kretzschmar, Kai, et al.
Publicado: (2018)

Proliferative activity in human breast cancer: Ki-67 automated evaluation and the influence of different Ki-67 equivalent antibodies
por: Fasanella, S, et al.
Publicado: (2011)

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group
por: Nielsen, Torsten O, et al.
Publicado: (2020)

Comparative Analysis of Bacteriophytochrome Agp2 and Its Engineered Photoactivatable NIR Fluorescent Proteins PAiRFP1 and PAiRFP2
por: Khan, Faez Iqbal, et al.
Publicado: (2020)

Immunolocalization of Ki-67 in different periodontal conditions
por: Preethi, Penubolu Lakshmi, et al.
Publicado: (2014)

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids
por: Lõhmussaar, Kadi, et al.
Publicado: (2020)

Quantum Dots-Based Quantitative and In Situ Multiple Imaging on Ki67 and Cytokeratin to Improve Ki67 Assessment in Breast Cancer
por: Yuan, Jing Ping, et al.
Publicado: (2015)

ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling
por: Barricelli, Barbara Rita, et al.
Publicado: (2019)

Independent Clinical Validation of the Automated Ki67 Scoring Guideline from the International Ki67 in Breast Cancer Working Group
por: Boyaci, Ceren, et al.
Publicado: (2021)

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry
por: Selmani, Zohair, et al.
Publicado: (2022)

Ki-67 and breast cancer prognosis: does it matter if Ki-67 level is examined using preoperative biopsy or postoperative specimen?
por: Choi, Soon Bo, et al.
Publicado: (2022)

Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
por: Yang, Qiutan, et al.
Publicado: (2021)

The unfolding of iRFP713 in a crowded milieu
por: Stepanenko, Olesya V., et al.
Publicado: (2019)

ASO Author Reflections: Pancreatic Neuroendocrine Tumor Recurrence and Survival Predicted by Ki67
por: Nieveen van Dijkum, Els J. M.
Publicado: (2018)

A comparative study between Ki67 positive versus Ki67 negative females with breast cancer: Cross sectional study
por: Bahaddin, Mowafak Masoud
Publicado: (2020)

Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation
por: Soares, Andreia, et al.
Publicado: (2010)

Chromogranin A, Ki-67 index and IGF-related genes in patients with neuroendocrine tumors
por: van Adrichem, R C S, et al.
Publicado: (2013)

Distinctive crypt shape in a sessile serrated adenoma/polyp: Distribution of Ki67-, p16(INK4a)-, WNT5A-positive cells and intraepithelial lymphocytes
por: Hisamatsu, Kenji, et al.
Publicado: (2017)

Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche
por: Langlands, Alistair J., et al.
Publicado: (2016)

Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells
por: Pleguezuelos‐Manzano, Cayetano, et al.
Publicado: (2020)

Ki-67 biomarker in breast cancer of Indian women
por: Patil, Amit V., et al.
Publicado: (2011)

Quantifying the Ki-67 Heterogeneity Profile in Prostate Cancer
por: Mesko, Shane, et al.
Publicado: (2013)

Ki-67 Expression in Hydatidiform Moles and Hydropic Abortions
por: Khooei, Alireza, et al.
Publicado: (2013)

Proliferating Trichilemmal Cyst: The Value Of Ki67 Immunostaining
por: Rangel-Gamboa, Lucia, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5eh76f3c1f3vsbg3rrs2d5s1l0